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Cleaved-CD97 Alpha (L530) Polyclonal Antibody
Varastossa

Cleaved-CD97 Alpha (L530) Polyclonal Antibody

Arvostelut

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  • Luokka:

    Liiketoiminta ja teollisuus > Tutkimus- ja laboratoriotuotteet

  • Tuotenro: 772-BT-AP01915-50ul
  • Koko: 50ul
  • Toimittaja: Gentaur
ADGRE5 (adhesion G protein-coupled receptor E5) encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of ADGRE5 may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for ADGRE5. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.