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TMPRSS11F Polyclonal Antibody

Arvostelut
181.00

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Varastossa
  • Luokka:

    Liiketoiminta ja teollisuus > Tutkimus- ja laboratoriotuotteet

  • Tuotenro:

    866-RD77208A-60uL

  • Koko: 60μL
  • Toimittaja: Gentaur
TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.